Effect of Plasmid Presence and Stability on Growth of Escherichia coli DH5α with Use of Drugs, Chemicals, and Radiation

Main Article Content

Dr. Praveen Kumar Vemuri

Abstract

Objective: The purpose of the study delineates the growth and plasmid stability of E. coli DH5α host system.
Materials and Methods: Different concentrations of drugs, chemicals, and various frequency of radiations were
subjected to the host system to verify the colony-forming units along with plasmid concentration and stability.
Results: Among chemicals, acridine orange showed the highest effect on growth of DH5α, while among the
drugs, danthrone showed maximum effect on the growth of the organism. Radiofrequency of 2 GHz and lowintensity
microwave radiation were recorded as the highest inhibitory effects. However, there is no significant
effect in growth observed in exposure to UV rays. Conclusion: The present work discussed that drugs, chemicals,
radiofrequency, and microwave radiation have a huge effect on the growth of organism and also on the concentration
and stability of plasmid.

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How to Cite
Vemuri, D. P. K. (2019). Effect of Plasmid Presence and Stability on Growth of Escherichia coli DH5α with Use of Drugs, Chemicals, and Radiation. Asian Journal of Pharmaceutics (AJP), 13(3). https://doi.org/10.22377/ajp.v13i3.3294
Section
ORIGINAL ARTICLES