Microsponge: A Novel Approach for Topical Drug Delivery of Anti Rheumatoid Drugs

Abstract

Microsponge is one of the developing fields of science innovation, which can be capable of both regulated drug
delivery and site-specific administration of drugs. The determination of the particular pharmaceutical formulations
and way of distribution for delivery of the medicament is strongly influenced by the physical and chemical
characteristics of the microsponge, such as the size of particles, distribution of particle size, transparency, and
surface structure. An innovative technique for topical medicine delivery has also emerged: The microsponge. The
topical methods further benefit from flexible formulations, more patient participation, increased safety and overall
performance, and attractive characteristics. Immunomodulatory rheumatoid arthritis requires long-term therapy
to control the condition. Long-term administration of the marketed oral dosage forms may result in liver damage.
The topical way may represent a good alternative method for medication delivery with better drug stability, less
adverse effects, and less frequent administration. Microsponges have the ability to entrap significant amounts of
dosage and may also alter medication release due to its porous and spongy nature.