@article{Seema_2019, title={Isolation, Characterization and Evaluation of Mimosa pudica Seed Mucilage as Pharmaceutical Additives}, volume={13}, url={http://asiapharmaceutics.info/index.php/ajp/article/view/3406}, DOI={10.22377/ajp.v13i04.3406}, abstractNote={<p>Aim: The aim of this present work was to isolate, characterized, and evaluate the natural plant-based<br />polysaccharides from the seeds of Mimosa pudica plant which belongs to family Mimosaceae. In pharmaceutical<br />industries large number of excipients is used which are obtained from natural sources, mucilage is one of<br />them. Mucilage and their derivatives are a group of polymers extensively used in pharmaceutical dosage<br />forms. Materials and Methods: The fresh M. pudica seeds were collected from Botanical Garden Greater<br />Noida India. The plant was authenticated at the pharmacognosy department by a scientist at National Institute<br />of Science Communication and Information Resources (NISCAIR) Delhi. (Authentication voucher no.<br />NISCAIR/RHMD/Consult/2019/3437-38) All other chemicals used were of analytical grade, and distilled<br />water was used throughout the experiments. M. pudica (family Mimosaceae), commonly known as sensitive<br />plant and widely used as herbal medicine in India, is widely available and has very low cost. It is diffuse<br />under shrub found widely in the tropical and subtropical parts of India. Seeds of M. pudica yield mucilage,<br />which is composed of d-xylose and d-glucuronic acid. Mimosa seeds mucilage hydrates and swells rapidly<br />on coming in contact with water. The present investigation involved isolation of mucilage from M. pudica<br />seeds commonly known as chhui mui followed by phytochemical and physicochemical evaluation. Results<br />and Discussion: The mucilage isolated from the seed of M. pudica will be useful as an excipient for oral<br />drug delivery systems as the results of phytochemical and physicochemical tests indicated the suitability of<br />mucilage for tablet dosage form as well as a suspending agent for suspension due to its flowability, weakly<br />acidic pH, swelling potential, and viscous in nature. The present study suggests that isolated mucilage from<br />the seeds of M. pudica showed good flow properties which is suitable for a direct compression formulation<br />and is non-irritating in nature to the mucosal membrane.</p>}, number={04}, journal={Asian Journal of Pharmaceutics (AJP)}, author={Seema, Mahor}, year={2019}, month={Nov.} }