@article{Kumar_2018, title={Stability Indicating Development and Validation of Ultraviolet Spectrophotometric Methods for the Simultaneous Estimation of Bromhexine and Cephalexin in their Combined Dosage Form}, volume={11}, url={https://asiapharmaceutics.info/index.php/ajp/article/view/1741}, DOI={10.22377/ajp.v11i04.1741}, abstractNote={Aim: The aim of this study is to develop two simple, rapid, accurate, economical validated spectrophotometric for simultaneous estimation of bromhexine and cephalexin in bulk and dosage form. Materials and Methods: The Method-I is first derivative spectrophotometric and Method-II is the simultaneous equation method. Both the methods were employed for the analysis of drugs bromhexine and cephalexin using methanol and ammonium hydrogen phosphate (pH 7.7) in the ratio of 60:40 as a diluent. Results and Discussions: Both the methods are used for the simultaneous determination of bromhexine and cephalexin at 2155 nm and 266.5 nm, respectively, over the concentration range of 0.2–1.2 μg/ml and 12.5–75 μg/ml with the correlation coefficient (r2) 0.9996 and 0.9994. Conclusions: The recovery studies confirmed the accuracy of proposed method and low-value standard deviation confirmed precession of method. The method is validated as per the International Council for Harmonization guidelines.}, number={04}, journal={Asian Journal of Pharmaceutics (AJP)}, author={Kumar, Dr. K. Kiran}, year={2018}, month={Feb.} }