@article{Ommi_2022, title={Evaluation of Fumonisins Contamination using Liquid Chromatography Mass Spectrometry in Corn Samples Collected from Different Locations}, volume={16}, url={https://asiapharmaceutics.info/index.php/ajp/article/view/4387}, DOI={10.22377/ajp.v16i2.4387}, abstractNote={<p>The aim of the study was to determine fumonisins (FMS) using liquid chromatography coupled with mass<br>spectrometry in maize. Materials and Methods: FMSs are mycotoxins frequently found in contaminated corn<br>samples. The presence of FMSs in corn samples should be continuously controlled to protect the population<br>form risks associated with its proven toxicity. About 24 corn samples were collected in different locations of<br>Andhra Pradesh such as harvesting area, storage area, and dumping area of godown for determination of<br>contamination by FMSs. Results and Discussion: The retention time of the well-defined peak of FMS B1 and<br>B2 was found 1.15 min and 2.59 min which is similar to the obtained method. Among 24 samples, about 7 corn<br>samples were found positive contamination by FMS when subjected to liquid chromatography-mass spectrometry<br>analysis. The high levels of FMS contamination were found in sample number 7(s-7) which is collected from the<br>dumping area of storage godown. The fungal damaged sample was found B1concentration of 242.11 μg/kg and<br>FB2 of 117.15 μg/kg. The concentration of FB1 is very high in the sample compared to the regulatory guidelines<br>limit. The low amount of FMS is identified in sample number 8(s-8) which is collected from the dumping area<br>and in damaged condition. FB1 concentration was found 15.0 μg/kg. The sample 4(s-4) is found contaminated<br>with FB2 with 15.780 μg/kg concentration. Conclusion: Based on the results, it can conclude that corn samples<br>collected from the dumping area of godown are found more contaminated with mycotoxin (FMS) than the other<br>sample collecting area such as storage area and harvesting area.</p>}, number={2}, journal={Asian Journal of Pharmaceutics (AJP)}, author={Ommi, Sailaja}, year={2022}, month={Jun.} }