@article{Mishra_2016, title={Mouth Dissolving Delivery System: A Novel Approach for Angina}, volume={10}, url={https://asiapharmaceutics.info/index.php/ajp/article/view/639}, DOI={10.22377/ajp.v10i2.639}, abstractNote={<p>Aim: The study aims to see the sights of potential of mouth dissolving tablets for improving the oral delivery<br />of nicorandil by the use of superdisintegrants. Materials and Methods: Fast dissolving tablets of nicorandil<br />successfully prepared by direct compression techniques using various concentrations of sodium starch glycolate,<br />croscarmellose sodium, and crospovidone (CP) as superdisintegrants. The optimized batch of fast dissolving<br />tablets of nicorandil were characterized for hardness, friability, in vitro disintegration, dissolution, stability<br />studies. Results and Discussion: In comparison to marketed immediate-release formulation, the formulation (F9)<br />was found to be faster in drug release profile as well as short disintegration time. The formulation F9 were found<br />to be stable in 6 months stability studies in different packing. Conclusion: Nicorandil tablets containing CP as a<br />superdisintegrant show faster disintegration and dissolution rate.</p>}, number={2}, journal={Asian Journal of Pharmaceutics (AJP)}, author={Mishra, Prerana}, year={2016}, month={Jun.} }