TY - JOUR AU - Fadilah, Fadilah PY - 2019/02/04 Y2 - 2024/03/28 TI - Differential Scanning Calorimeter Profiling for the Determination of Nanoparticle Ethanol Extract of Clove (Syzygium aromaticum L.) Toward Michigan Cancer Foundation-7 Human Breast Cancer Cell Lines JF - Asian Journal of Pharmaceutics (AJP) JA - AJP VL - 12 IS - 04 SE - ORIGINAL ARTICLES DO - 10.22377/ajp.v12i04.2950 UR - https://asiapharmaceutics.info/index.php/ajp/article/view/2950 SP - AB - Aim: This research was conducted to evaluate in vitro assay of nanoparticles ethanol extract of cloves toward Michigan Cancer Foundation-7 human breast cancer cell lines. Materials and Methods: In this research, we have synthesized bud clove extract nanoparticles and analyzed with differential scanning calorimetry. The cytotoxic activity of extract, nanoparticles, and its bioactive component was investigated with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and analyzed by ELISA reader. Results: The in vitro test showed that the IC50 values of the extract and the nanoparticles were 20.13 μg/mL and 7.6 μg/mL, respectively. Conclusion: The ethanol extracts of clove (Syzygium aromaticum L.) could be formulated in nanoparticles form. From cytotoxicity assay, nanoparticle of clove extract showed better cytotoxic activity than the ethanol extract. ER -