Nanoparticle: Drug delivery system for cancer therapy

Nisha Mary Joseph, Pramod Kumar Sharma

Abstract


Nanoparticle has emerged as a promising strategy for the efficient delivery of drugs used in the treatment of cancer by avoiding the reticuloendothelial system, utilizing the enhanced permeability and retention effect and tumor-specific
targeting. Delivery methods using nanoparticle are highlighted including both degradable and non-degradable polymers. The preparation techniques include emulsion polymerization, micelle polymerization, desolvation of macromolecule, and
emulsion-solvent evaporation methods.The particle size of the polymeric nanoparticle is in the nanometer range (10-1000 nm) and is dependent on the method of preparation employed.


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DOI: http://dx.doi.org/10.22377/ajp.v2i3.183

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