Dermal delivery of drugs using different vesicular carriers: A comparative review
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Abstract
skin. Some formulations do not penetrate through the stratum corneum and some pass through the skin very quickly.Therefore, there is need to develop a strategy to deliver drugs to the dermis for better management of these conditions.
Vesicular systems like liposomes, niosomes, ethosomes and transfersomes have been used by many researchers to localize drugs in the dermal layer and have been fairly successful. Some vesicles were found to be more effective in retaining drug
to the skin and some were more effective in transdermal delivery. This article summarizes and compares the work done in the last decade on this topic and provides a conclusion.
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