Antiviral Efficacy of Tinospora cordifolia – A Review

Abstract

Since ages, plants have had a pivotal role as medicine due to their therapeutic value. Tinospora cordifolia is a
well-known plant with versatile medicinal properties including hypoglycemic, anti-inflammatory, antioxidant,
immunomodulatory, and antimicrobial, which can be attributed to its secondary metabolites. Viral infections
constitute a major faction of human diseases. Developing efficient and novel therapeutic agents to combat viral
diseases is an ongoing process, wherein plant-derived natural products are a potential source. T. cordifolia has
been explored for its use in viral infections as an immunomodulatory and antiviral agent. Bioactive components of
the plant, such as berberine, tinosponone, tinocordiside, isocolumbin, magnoflorine, tinosporin, and cordiofoliside
have been reported to exhibit antiviral efficacy. The present review summarizes the efficacy of T. cordifolia as an
anti-viral agent and its role in combating viral infections.