Niosomes as Efficient Nanocarriers for Targeted Drug Delivery

Abstract

The localization of pharmacological molecules to stick locations is made possible by target-specific drug delivery
systems with its bi-layer structure made of non-ionic surfactants, the noisome vesicular system can temporarily
increase a drug’s bioavailability in a specific location. Scientists who study drug delivery systems have been highly
concerned with the creation of vesicles as a means of enhancing medication delivery in recent years. Niosomes’
amphiphilic character enhances their ability to effectively encapsulate hydrophilic or lipophilic medications. It
is common practice to add additional ingredients, like cholesterol, to preserve the niosomes’ structural stiffness.
When comparing the great chemical stability and effectiveness of the replacement with niosomes, liposomes use
vesicles for medicinal and therapeutic applications, which have several advantages. They boost the therapeutic
efficiency of drug molecules by keeping the medicine from exiting circulation too quickly, shielding it from its
genetic environment, and lessening its effect on target cells. This research concentrated on current advancements
in the distribution of niosomal medications, potential advantages over other delivery systems, building techniques,
characterization techniques, and recent research that is noisy. The use of niosomes in nanotechnology has the
potential to yield highly targeted, non- infective, and non-cancer agents. Proniosomes and aspasomes are a few
examples of novel concepts that have been used to enhance niosomes’ drug delivery capabilities. Niosomes
are also beneficial as a living component of vaccines and for diagnostic tests. Therefore, further research and
development are required in these areas to produce the niosomal preparations that are now on the market.