A Review on Microspheres as Drug Carriers

Abstract

Orally modified-release multiple-unit dosages have consistently shown themselves to be a more successful
therapeutic choice than other dosage types. Novel medication delivery systems have several advantages over
conventional multidose therapy. Current trends indicate that the use of microparticles in drug delivery systems
can result in regulated or delayed release formulations for oral use with minimal risk of dose dumping, variable
blending to achieve different release patterns, and predictable and short stomach residence time. In addition to
their prolonged release, microspheres garnered significant interest for their capability to specifically target drugs.
It has been demonstrated that oral modified-release multiple-unit dosage is a more efficacious treatment option in
comparison to traditional or quick-release single-unit dosage forms. Innovative drug delivery methods are superior
to traditional multidose therapy in a number of ways. According to current trends, the use of microparticles in drug
delivery systems can lead to formulations that are regulated or released gradually for ingestion with a low risk of
dose dumping, blending that can be adjusted to achieve diverse release patterns, and a stomach residence period
that is predictable and brief. In addition to their extended release, microspheres attracted a lot of attention due to
their capacity to target medications precisely.