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Introduction: The current novel research work aims in preparing various formulations of antibacterial tooth
powder and evaluates for the best formulation among the fabricated formulations. Materials and Methods: The
antibacterial agents chosen were thymol and camphor, bentonite for detoxification, calcium carbonate for
abrasion, peppermint oil for flavoring, sodium saccharin for sweetness, and sodium lauryl sulfate for foaming.
A total of six formulations were done by naming F1 to F6 with various combinations of all the agents. Carr’s
index, angle of repose, moisture content determination, foaming power determination, physical appearance/
visual inspection, pH determination, bulk density and tapped density determination, and in vitro antibacterial
activity against Staphylococcus aureus by agar well-diffusion method were all used to assess each formulation.
Results and Discussion: Based on a comprehensive analysis of all formulation evaluations, F3 is deemed the
best due to its superior antibacterial activity, foaming power, and all other evaluations. A 24-h incubation period
confirms the antibacterial activity. Conclusion: F3 might yield extremely positive and encouraging outcomes in
achieving the current work’s goal.
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