Unraveling Glioblastoma: An Integrative Review of Genomics, Immunology, and Clinical Approaches
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Abstract
Children are at a lower risk of developing glioblastoma compared to adults. Although it is uncommon, existing
studies indicate that juvenile glioblastoma is markedly different from its adult counterpart. These variations are
related to molecular genetics, the efficacy of supplementary treatments, and potentially the results following
therapy. Recent advancements in translational research have provided a significant number of new insights into
juvenile glioblastomas, presenting substantial opportunities for future therapeutic approaches. This chapter seeks
to emphasize the main clinical characteristics of pediatric glioblastoma, incorporating recent advancements in
clinical and laboratory research.
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