Adjunctive Use of Ozonated Water andOzonated Olive Oil with Scaling andRoot Planing in Chronic Periodontitis: AComparative Clinical Study

Abstract

Introduction: In dentistry, gingival and periodontal disorders are a primary source of suffering. All kinds of
ozone reduce or treat the majority of the contributory and causative causes. All phases of gingival and periodontal
disorders can benefit from ozone, which is well known for its antibacterial and tissue-regenerating qualities.
Comparing and assessing the effectiveness of ozonated water (OW) and ozonated olive oil (OOO) as a supplement
to scaling and root planing (SRP) in patients with chronic periodontitis is the goal of this study. Methods: A total
of 30 systemically healthy patients aged 35–55 years with chronic periodontitis were enrolled for this study. After
SRP, participants were randomly allocated to Group 1 (n = 15, OW irrigation) or Group 2 (n = 15, OOO application),
with allocation managed by an independent researcher. Results: OW showed superior periodontal improvement at
3 months, with greater probing pocket depth (PPD) reduction (5.40 mm vs. 6.57 mm), better CAL gain (5.80 mm
vs. 6.40 mm; P < 0.001), and improved gingival recession (0.33 mm vs. 0.57 mm; P = 0.015) compared to
ozonated olive oil. Conclusion: This randomized clinical trial demonstrated that both OW and ozonated olive oil,
when used as adjuncts to SRP, resulted in significant improvements in PPD and clinical attachment level within
their respective groups after 3 months. However, the intergroup comparison revealed a significant difference with
OW at 3 months, indicating that OW was effective in enhancing periodontal healing.