Natural Compound Apigenin Ameliorates Skin Inflammation
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Abstract
The skin functions as the primary protective barrier, mitigating oxidative stress induced by ultraviolet radiation
and other components from the environment. It blocks viruses, allergens, and other harmful agents from entering
the body. An excessive immune response to these substances can lead to severe skin conditions such as dermatitis,
vitiligo, and cancer. The flavonoid family includes kempferol, luteolin, quercetin, and apigenin. Due to its
numerous biological effects, apigenin has been used as a dietary supplement. Studies have demonstrated that it
alleviates skin inflammation by suppressing key inflammatory markers and molecular pathways. In this review, we
discuss the current understanding of skin inflammation and how apigenin formulation reduces skin inflammation.
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