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basis of the comparative study, resin 214 was selected for taste masking property. Disintegrant croscarmellose (5% wt/wt) gave the minimum disintegration time in comparison to crosspovidone and sodium starch glycolate. The batch of tablet
containing Pearlitol SD and Avicel (PH102) in the ratio 60:40 and 5% (wt/wt) Croscarmellose showed faster disintegration i.e. 32 s, as compare to marketed tablet. It also revealed rapid drug release (t80, 6 min) in SGF compared with marketed formulation (t80, 9 min).
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