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percentage of mosapride content from the beads was determined by high-performance liquid chromatography (HPLC) and ranged from 97.9 ï‚± 0.08 to 99.6 ï‚± 0.01. The in-vitro percentage release of mosapride from the beads at the end of 14 hours ranged from 90.0 ï‚± 0.2 to 99.5 ï‚± 0.12. The formulated beads in formulations 1 and 3 were sealed in vials and kept for 90 days at 40Â°C / 75% RH. After 90 days of exposure the percentage drug content was found to be 99.2 ï‚± 0.04. The Floating beads designed for the gastroretentive dosage form could be suitable for controlled drug delivery.
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