Formulation, characterization, and evaluation of matrix-type transdermal patches of a model antihypertensive drug

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V G Jamakandi
J S Mulla
B L Vinay
HN Shivakumar


T he present investigation was aimed to evaluating the possibility of using different polymeric grades of hydroxy propyl
methyl cellulose (6cps, 15cps, and K4M) for the development of transdermal drug delivery systems of nicorandil,
an antianginal drug. Prepared matrix-type patches were evaluated for their physicochemical characterization followed by
in vitro evaluation. Selected formulations were subjected for their ex vivo studies on porcine ear skin.


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Jamakandi, V. G., Mulla, J. S., Vinay, B. L., & Shivakumar, H. (2014). Formulation, characterization, and evaluation of matrix-type transdermal patches of a model antihypertensive drug. Asian Journal of Pharmaceutics (AJP), 3(1).


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