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incorporated as a gasâ€generating agent.The effect of different concentrations of polymers on drug release profile and floating properties were investigated. Comparable release profiles between the commercial product and the designed system were obtained. The matrix formulations were evaluated for physical parameters, drug release by in vitro dissolution studies and in vitro buoyancy studies. Surface characteristics, drugâ€excipient interactions and crystal morphology of optimized formulations were evaluated by SEM analysis and DSC studies.
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