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two formulations and for only 4 weeks in the last one. However, PVP-I was only stable for a period of 3 weeks when it was the only active ingredient as in F4. The pH of the formulations remained constant for the entire study period for all
formulations. No changes in viscosity, smell or color of all the toothpaste formulations were observed. The compounding of PVP-I toothpaste in order to achieve oral hygiene can be achieved successfully. Attention should be made by practicing pharmacists with regard to the exact expiry dates of the obtained formulations.
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